Laboratory Azatyan
Tissue Microarrays

Tissue Microarrays (TMA) technology is a modern, high-throughput technology widely used for biomedical research studies. Briefly, TMA presents a way to unite/merge multiple tissue samples in a single platform. Such samples can represent, for example, many samples of the same cancer types, or various cancer subtypes, or various normal tissues, etc.

Generally, biomedical experiments assessing a presence of certain biomarkers require hundreds and thousands of tissue samples to be investigated: for example, stained and assessed microscopically, or hybridized with test molecules. For that, large series of individual experiments are performed. Such series of experiments require a lot of time and a lot of consumables, many of which are very expensive. Even more importantly, performing many individual experiments cause some variability, which introduces a bias into interpretation. By uniting many tissue samples in a single TMA platform, a researcher can assess them in a single run, - thus saving precious time, expensive consumables, and reducing inter-experiment variability.

TMA technology is thus most useful in research experiments aiming developing and validating diagnostic and monitoring kits and treatment approaches. In particular, TMAs are extremely useful to test specificity of therapeutic antibodies – a modern class of drugs recently developed and now successfully used to treat various cancer subtypes; it is also applied in inflammatory disorders, such as psoriasis. Laboratory Azatyan is providing researchers high quality TMAs of standard and custom design. Research area covered by our services is mostly related to cancer (including lung, colorectal, breast cancer, lymphoma, etc.) but also includes inflammatory, dermatological and other disorders where tissue is affected in a various way, and where diagnostic, monitoring and therapeutic means need to be developed.